Small nucleolar RNA SNORA17
| Small nucleolar RNA SNORA17 | |
|---|---|
 Predicted secondary structure and sequence conservation of SNORA17 | |
| Identifiers | |
| Symbol | SNORA17 |
| Alt. Symbols | snoACA17 |
| Rfam | RF00560 |
| Other data | |
| RNA type | Gene; snRNA; snoRNA; HACA-box |
| Domain(s) | Eukaryota |
| GO | GO:0006396 GO:0005730 |
| SO | SO:0000594 |
| PDB structures | PDBe |
In molecular biology, SNORA17 (also known as ACA17) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.[1] Specifically, it is predicted to guide pseudouridylation of the 28S rRNA at positions U4659 and U4598. It shares the same host gene together with ACA43.
There are many closely related sequences that do not appear to have conserved H and ACA boxes, and may be pseudogenes.
References
[edit]- ^ Kiss AM, Jády BE, Bertrand E, Kiss T (July 2004). "Human box H/ACA pseudouridylation guide RNA machinery". Molecular and Cellular Biology. 24 (13): 5797–807. doi:10.1128/MCB.24.13.5797-5807.2004. PMC 480876. PMID 15199136.
Further reading
[edit]- Ofengand J, Bakin A (February 1997). "Mapping to nucleotide resolution of pseudouridine residues in large subunit ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts". Journal of Molecular Biology. 266 (2): 246–68. doi:10.1006/jmbi.1996.0737. PMID 9047361.
External links
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